在患有阻塞性睡眠呼吸暂停综合征的患者中,眼睛表面参数的改变
Linlin Hao1, Qingfen Tian2, Shaohua Liu1
1Department of Ophthalmology, The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, China.
Frontiers in medicine
|October 6, 2023
概括
阻塞性睡眠呼吸暂停综合征 (OSAS) 患者通常会出现干眼症状. 这些发现凸显了在患有OSAS的个体中增加眼睛表面护理的需要.
科学领域:
- 眼科医生 眼科 眼科
- 睡眠医学 睡眠医学
- 眼睛表面疾病 眼睛表面疾病
背景情况:
- 阻塞性睡眠呼吸暂停综合征 (OSAS) 与全身炎症和潜在的眼睛表面变化有关.
- 了解OSAS对眼睛健康的影响对于全面的患者管理至关重要.
研究的目的:
- 评估和比较患有阻塞性睡眠呼吸暂停综合征 (OSAS) 的患者的眼睛表面参数与健康对照组.
- 为了调查眼睛表面参数在OSAS.不同严重程度的差异.
主要方法:
- 一项涉及27名OSAS患者和44名健康志愿者的横截面研究.
- 眼睛表面评估包括眼半径高度 (TMH),非侵入性眼破裂时间 (FNITBUT,MNITBUT),梅博米腺脱落 (Meiboscore),希尔默I测试 (SIT),角膜光染色 (CFS),部分闪率 (PBR),脂质层厚度 (LLT) 和OSDI问卷.
- OSAS患者被分为轻度至中度和严重的组.
主要成果:
- 与对照组相比,OSAS患者表现出明显较低的TMH,FNITBUT,MNITBUT,以及较高的OSDI,CFS,Meiboscore和PBR.
- 严重的OSAS比轻度至中度的OSAS显示出更高的CFS,比对照组显示出更低的MNITBUT.
- 梅博斯core与呼吸暂停-呼吸暂停指数 (AHI) 有正相关;FNITBUT和MNITBUT与BMI有负相关.
结论:
- OSAS患者表现出干眼症的倾向,与健康个体不同.
- 对于被诊断患有OSAS的患者,建议进行例行眼表面评估和护理.
- OSAS的严重程度会影响眼睛表面的特定参数,因此需要有针对性的干预措施.
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