患有COVID后疾病的患者的眼睛运动
Valldeflors Vinuela-Navarro1, Joan Goset1, Mikel Aldaba1
1Center for Sensors, Instruments and Systems Development, Universitat Politècnica de Catalunya, Rambla Sant Nebridi 10, Terrassa 08222 (Barcelona), Spain.
Biomedical optics express
|October 6, 2023
概括
后COVID-19状态 (PCC) 可以损害眼睛运动控制,影响分眼延迟和固定稳定性. 在严重病例中,瞳孔反应也会有所不同,这表明COVID-19的神经影响.
科学领域:
- 神经科学是一个神经科学.
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
背景情况:
- 神经系统疾病可能会影响眼睛的运动控制.
- COVID-19对眼运动功能和瞳孔反应的影响在很大程度上是未知的.
- 后COVID-19状态 (PCC) 可能涉及潜在与神经变化相关的认知缺陷.
研究的目的:
- 调查COVID-19后病情 (PCC) 和认知缺陷的个体眼运动功能和瞳孔反应的差异.
- 为了比较对照组和患有轻度或重度COVID-19病史的个体之间的眼动和瞳孔反应参数.
主要方法:
- 眼睛跟踪被用来记录动,平滑的追逐,固定,合和瞳孔反应.
- 眼运动和瞳孔参数被计算用于分析.
- 从16个对照组,38个轻度COVID-19 (在家康复),和19个严重COVID-19 (住院) 参与者中收集了数据.
主要成果:
- 与对照组 (183±54毫秒) 相比,在轻度 (236±83毫秒) 和严重 (227±42毫秒) 的COVID-19组中,顺序延迟时间显著更长.
- 固定稳定性,以双变边形圆面积来衡量,在轻度COVID-19组 (0.80±1.61°2) 与对照组 (0.36±0.65°2) 中较差.
- 与对照组 (51.7±22.0%/49.1±20.7%) 相比,严重的COVID-19参与者 (39.7±12.7%/31.6±12.7%) 的瞳孔区域缩小/扩大的百分比减少了.
结论:
- 患有COVID-19后疾病的个人表现出明显的眼运动和瞳孔变化.
- 这些发现表明COVID-19后持续症状的潜在神经基础.
- 描述这些变化可能有助于理解PCC的各种病理生理机制.
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