扩展和可调节的视野可变间扫描时间分析的氨酸扫描扫描扫描源光学连贯性断层扫描血管学
Toshihiro Mino1,2, Yoshikiyo Moriguchi2, Masato Tamura2
1Topcon Advanced Biomedical Imaging Laboratory, Topcon Medical Systems, 111 Bauer Drive, Oakland, NJ 07436, USA.
Biomedical optics express
|October 6, 2023
概括
一个新的氨酸扫描协议使广场光连贯断层扫描血管造影 (OCTA) 和视网膜血流速度成像成为可能. 这种方法提高了扫描范围,并纠正了眼睛的运动,有助于微血管研究.
科学领域:
- 眼科医生 眼科 眼科
- 生物医学成像技术 生物医学成像技术
- 医疗技术 医疗技术 医学技术
背景情况:
- 光学连贯断层扫描血管造影 (OCTA) 对于视网膜成像至关重要.
- 评估视网膜血流速度和微血管变化对于诊断眼睛疾病至关重要.
- 目前的OCTA方法在扫描范围和运动工件校正方面存在局限性.
研究的目的:
- 引入和验证一个新的扫描协议,氨酸扫描,用于广场OCTA.
- 为了使相对视网膜血流速度成像使用可变间扫描时间分析 (VISTA).
- 为了探索健康人眼中的微血管流量参数.
主要方法:
- 用400kHz扫描源激光进行重复循环扫描,间扫描时间短 (1.28ms).
- 氨酸扫描协议具有螺旋移动的扫描中心,可扩展可调节的扫描范围.
- 使用数据冗余的先进的运动校正算法被实施,以消除文物.
主要成果:
- 氨酸扫描成功实现了广场OCTA和视网膜相对血流速度成像.
- 维斯塔分析允许在表面和深层视网膜层中计算血液流动速度.
- 流速的比率被用来分析健康受试者的微血管参数.
结论:
- 氨酸扫描协议是广场OCTA和视网膜血流分析的一个有希望的进步.
- 这种技术提供了扩展的扫描范围和有效的运动器件校正.
- 它为调查视网膜微血管健康和疾病提供了一个新的工具.
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