普得尼索隆剂量与拔牙时延迟愈合之间的潜在关系:一项回顾性研究
Hiroyuki Hato1, Ken-Ichiro Sakata1, Haruhisa Watanabe1
1Department of Oral Diagnosis and Medicine, Faculty of Dental Medicine, Hokkaido University, Sapporo, Japan.
Journal of dental sciences
|October 6, 2023
概括
超过8.0毫克/天的普雷尼索隆剂量和X射线上的骨质硬化变化与延迟拔牙口愈合有关. 这一发现有助于识别患有较差治愈结果风险较高的患者.
科学领域:
- 在口腔外科手术中.
- 药理学 药理学是指药理学的学科.
- 放射学 放射学是一门学科.
背景情况:
- 拔牙口的延迟愈合是使用普得尼索隆的患者的已知的并发症.
- 确定特定的普得尼索隆剂量和相关因素对于管理这些患者至关重要.
研究的目的:
- 为了确定与延迟提取插座愈合相关的普雷迪尼索隆的特定剂量.
- 确定其他可能导致服用普得尼索隆的患者愈合延迟的因素.
主要方法:
- 一项对80名患者进行的回顾性研究,这些患者在服用口服普雷迪尼索隆时接受了牙拔除.
- 患者背景和普得尼索隆剂量之间的比较,治疗延迟和没有延迟的组.
主要成果:
- 在延迟愈合组中观察到更高的普雷迪尼索隆剂量.
- 每天8.0毫克或更高的剂量是延迟愈合的显著预测因素 (OR,10.8).
- 在X射线上的骨质硬化变化也与延迟愈合有显著的相关性 (OR,10.3).
结论:
- 超过8.0毫克/天的普雷迪尼索隆剂量是延迟提取口愈合的关键因素.
- 骨质硬化变化的放射性证据是延迟愈合的另一个重要风险因素.
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