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噪音不敏感的体积融合方法用于增强的光声学显微镜

Sihang Li^1,2, Hao Wu², Hongyu Zhang²

¹Nanchang University, School of Information Engineering, Nanchang, China.

Journal of biomedical optics

|October 6, 2023

概括

这项研究引入了一种具有成本效益的体积光声成像方法,以扩展光学分辨率光声显微镜 (OR-PAM) 的视野深度 (DoF). 这种新的方法可以提高成像深度,而不影响分辨率,从而改善OR-PAM.

科学领域:

生物医学光学生物医学光学
医疗成像医学成像
摄影声学显微镜的使用

背景情况:

光声学成像技术将光学对比与声学透相结合.
光学分辨率光声显微镜 (OR-PAM) 由于强烈的激光聚焦,具有有限的景深 (DoF).

研究的目的:

为大容量成像开发一种低成本的体积光声信息融合方法.
在不牺牲横向分辨率的情况下,扩展OR-PAM的视场深度 (DoF).

主要方法:

一个3D拉普拉斯运算符用于焦点检测,以构建初始决策地图.
多数过器用于一致性验证和高斯过器用于地图光滑.
融合多焦点船舶数据以创建扩展的DoF图像.

主要成果:

拟议的方法将DoF扩大了1.7.的因素.
侧面分辨率是保持没有牺牲.
该方法在各种噪声级别中显示出有效性和稳定性.

结论:

开发的方法有效地扩展了OR-PAM的DoF.
这种技术在不同的噪音条件下是坚固的.
能够进行具有成本效益的,大量的光声学成像.

关键词:

扩大了场域深度的扩展.噪音不敏感,对噪音不敏感.摄影声学显微镜的使用方法空间域是一个空间域.大量的核聚变.

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