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相关概念视频

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Redox Titration: Iodimetry and Iodometry01:23

Redox Titration: Iodimetry and Iodometry

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Iodometry and iodimetry are analytical methods used to determine the concentration of oxidizing or reducing agents using iodine. In iodometric titrations, the oxidizing analyte solution is usually acidified and treated with an excess of iodide ions, which generates an equivalent amount of iodine in equilibrium with triiodide. The released iodine is subsequently titrated directly against a standardized reducing agent. As the dilute iodine color becomes pale yellow, a few drops of freshly...
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Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Synthesis and Functions of Calcitonin00:51

Synthesis and Functions of Calcitonin

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Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
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Therapeutic Index01:13

Therapeutic Index

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The therapeutic index of a drug is a key parameter in pharmacology that quantifies the relative safety of a drug by calculating the ratio between the dose that causes toxicity in half the population (50%) to the dose that proves to be effective for half the population (50%). It provides a spectrum of doses for a particular drug ranging from effective to potentially toxic. To illustrate, consider an anticoagulant agent like warfarin. It possesses a narrow window within its therapeutic index to...
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相关实验视频

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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
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诱导的甲状腺功能障碍:科学测量研究和可视化分析分析.

Boshen Gong1, Xichang Wang1, Chuyuan Wang1

  • 1Department of Endocrinology and Metabolism, Institute of Endocrinology, National Health Council (NHC) Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.

Frontiers in endocrinology
|October 6, 2023
PubMed
概括
此摘要是机器生成的。

这项研究分析了2000-2022年对诱导的甲状腺功能障碍的研究. 关键发现揭示了趋势,并突出了孕妇,流行病学和甲状腺健康的缺乏症的未来研究.

关键词:
甲状腺功能过强症 甲状腺功能过强症甲状腺功能低下症 甲状腺功能低下症的含量是多少孕妇 孕妇 孕妇 孕妇科学测量研究科学测量研究甲状腺功能障碍 甲状腺功能障碍视觉化 分析 分析

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科学领域:

  • 内分泌学和甲状腺研究研究.
  • 圣经计量学和科学计量学

背景情况:

  • 对于甲状腺激素的合成至关重要.
  • 缺乏可以导致流产和死产.
  • 过多的摄入会导致甲状腺功能障碍,包括甲状腺功能过高和甲状腺功能低下.

研究的目的:

  • 想象过去二十年来诱导的甲状腺功能障碍的研究热点和趋势.
  • 为了指导这个领域的未来研究方向.
  • 为学者提供对该领域发展的快速了解.

主要方法:

  • 从2000年到2022年间,科学计量分析了2986篇出版物.
  • 数据从Web of Science核心集合中获取,使用特定的和甲状腺功能障碍的搜索术语.
  • 使用CiteSpace,VOSviewer和其他软件分析国家,机构,关键词,参考文献和期刊.

主要成果:

  • 对诱导的甲状腺功能障碍的研究显示有三个发展阶段:初始 (2000 - 2009年),稳定 (2010 - 2016年) 和快速 (2016 - 2022年).
  • 临床内分泌和新陈代谢杂志获得了最多的共同引用.
  • 中国医学大学发表的论文最多;顶级研究集群包括孕产妇低甲状腺血,亚临床甲状腺功能障碍和大脑发育.

结论:

  • 未来的研究应该专注于孕妇,流行病学和缺乏症.
  • 这项研究强调了在维持甲状腺功能的关键作用.
  • 科学度分析有效地揭示了诱导的甲状腺功能障碍的研究结构和趋势.