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初级精神病中的负面症状和认知缺陷:精神病康复中心的观察研究
Francesco Franza1, Alessia De Paola, Francesco Papa
1Rehabilitation Center "Villa dei Pini", 83100 Avellino, Italy, francescofranza60@gmail.com.
Psychiatria Danubina
|October 6, 2023
概括
负面症状和认知缺陷显著影响精神病患者. 该研究观察到精神病医院住院患者中这些问题之间的相关性,在COVID-19大流行期间稳定下来.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
背景情况:
- 负面症状 (NSs) 和认知缺陷 (CDs) 是初级精神病的核心挑战.
- 这些症状显著损害了患者的生活质量和功能结果.
- COVID-19 流行病可能影响了这些症状的表现和相互作用.
研究的目的:
- 评估精神病医院住院患者中NSs的患病率.
- 在COVID-19大流行期间评估NS和CD之间的关系.
- 在两个观察期内检查这种关系的变化.
主要方法:
- 观察性研究设计.观察性研究设计.
- 包括来自精神科康复机构的住院患者.
- 使用积极和消极综合征量表 (PANSS - FSNS),简短的消极症状量表 (BNSS) 和Epititrack进行症状评估.
主要成果:
- 在最初的观察期内,在NSs和CDs之间发现了显著的相关性 (PANSS - FSNS p=0.001;BNSS p=0.023;Epitrack p=0.00).
- 在第一和第二个观察期之间,NSs和CDs之间的关系显示稳定 (PANSS - FSNS:p=0.094;BNSS p=0.466;Epitrack p=0.026).
结论:
- 在精神病患者中,NS和CD显著相互关联.
- 随着时间的推移,COVID-19大流行背景并没有导致观察到的NSs-CDs关系发生显著变化.
- 需要进一步的研究来了解长期影响和潜在的干预措施.
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