睡眠变化,睡眠不规则性和夜间血压下降
Yanyan Xu1,2, Vernon A Barnes1, Ryan A Harris1
1Georgia Prevention Institute (Y.X., V.A.B., R.A.H., M.A., C.W., K.N., J.L., R.C., S.S., X.W.), Medical College of Georgia, Augusta University, GA.
Hypertension (Dallas, Tex. : 1979)
|October 6, 2023
概括
日常睡眠模式的偏差,如不规则的睡眠时间和时间,与夜间血压下降的减少有关. 睡眠不规则的种族差异可能解释了黑人和欧洲裔美国成年人血压下降的差异.
科学领域:
- 时间生物学 时间生物学
- 心血管健康 心血管健康
- 睡眠科学 睡眠科学
背景情况:
- 昼夜节律对于调节人类生物功能至关重要.
- 睡眠-清醒周期的规律性会影响生理过程,包括血压调节.
- 现有的研究表明,心血管健康结果的种族差异.
研究的目的:
- 为了研究每日睡眠-清醒周期变化对夜间血压 (BP) 下降的影响.
- 为了确定睡眠模式变化的种族差异是否有助于血压下降的种族差异.
主要方法:
- 利用了来自365名成年人的24小时门诊血压监测和7天加速计数据.
- 包括一个多元化的队列:52.6%的黑人参与者和47.3%的欧洲裔美国人.
- 使用睡眠持续时间的标准偏差和睡眠中点量化睡眠变化.
主要成果:
- 睡眠不规则性增加 (睡眠中点的SD) 与夜间血压下降的减少显著相关.
- 睡眠变化增加 (睡眠持续时间的SD) 也与夜间血压下降相关.
- 睡眠不规则的种族差异占BP浸泡中观察到的种族差异的29.2%.
结论:
- 睡眠的变化和不规则性独立地与血压下降有关.
- 睡眠不规则部分解释了血压下降的种族差异.
- 研究结果表明,针对睡眠模式的潜在干预措施可以减少健康差异.
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