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在接受凯托洛拉克止痛药的患者中,桃体切除术后出血
D Yadav1, B Dangol1, N Shrestha1
1Department of ENT-HNS, Patan Hospital, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal.
Kathmandu University medical journal (KUMJ)
|October 6, 2023
概括
凯托洛拉克在小儿桃体切除术后的疼痛管理中是安全的,没有增加出血风险. 在成年人中,建议谨慎使用,特别是在复发性桃体炎的情况下,由于观察到出血的发生率.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 药理学 药理学是指药理学的学科.
- 外科手术的结果
背景情况:
- 凯托洛拉克是一种非类固醇抗炎药物 (NSAID),为桃体切除术后的疼痛提供了阿片类药物的替代品.
- 人们对凯托洛拉克有可能增加桃体切除术后出血风险存在担忧.
- 目前的文献缺乏关于ketorolac在桃体和腺手术恢复中的使用的共识.
研究的目的:
- 为了确定术后桃体切除术后出血的发生率,在接受术后桃体切除术的患者中.
- 评估基托洛拉克在接受桃体和腺手术的儿科和成人患者出血方面的安全性.
主要方法:
- 术后接受凯托洛拉克治疗的患者的回顾性图表审查.
- 在尼泊尔帕坦卫生科学学院ENT-HNS部门进行的研究 (2013年4月 - 2019年5月).
- 分析儿科 (<18岁) 和成人 (≥18岁) 群体的出血率.
主要成果:
- 103名患者接受了手术后的凯托洛拉克;45名为儿科,58名为成人.
- 15名患者 (14.6%) 经历了桃体切除术后的出血:4名儿科和11名成人.
- 所有需要为出血进行手术的5名患者都是患有复发性桃体炎的成年人;没有人需要输血.
结论:
- 凯托洛拉克的使用与儿童的桃体切除术后出血风险增加无关.
- 在桃体和腺相关手术后,Ketorolac可以安全地用于儿科患者.
- 在成年患者中,特别是那些因桃体炎复发而接受手术的患者中,由于观察到的出血率,应该谨慎使用凯托洛拉克.
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