胆囊切除术和怀孕期间的ERCP:一项全国性的基于登记册的研究
Jonas Hedström1,2, Johan Nilsson3,4, Bodil Andersson1,2
1Department of Surgery.
International journal of surgery (London, England)
|October 6, 2023
概括
胆结石干预措施,如胆囊切除术 (胆囊切除术) 和ERCP (内镜逆行胆管松造影) 在怀孕期间是安全的. 在这些程序中,怀孕并不是不良事件的重要风险因素.
科学领域:
- 胃肠病学 胃肠病学
- 肝胆道手术 肝胆道手术
- 产科 产科 产科 产科 产科
背景情况:
- 在怀孕期间对胆结石病的治疗带来了独特的挑战.
- 虽然胆囊切除术和ERCP通常被认为是安全的,但对它们在孕妇患者的应用仍然存在担忧.
- 这项研究解决了围绕妊娠期胆结石干预结果的不确定性.
研究的目的:
- 评估胆囊切除术和孕妇ERCP的安全性和结果.
- 将这些结果与生育年龄的非怀孕妇女的结果进行比较.
- 为了确定怀孕是否是胆结石干预后并发症的独立风险因素.
主要方法:
- 从瑞典胆结石手术注册局和ERCP的数据进行了回顾性分析.
- 包括18-45岁的女性患者,接受胆囊切除术,ERCP或两者兼而有之.
- 怀孕和非怀孕患者队伍之间的结局的比较.
主要成果:
- 总共分析了21,328名患者,其中包括291名接受胆囊切除术的孕妇患者和63名接受ERCP的孕妇患者.
- 怀孕患者在30天的胆囊切除术后出现了更多的并发症,但在调整后,怀孕并不是一个显著的风险因素.
- 对于胆囊切除术,在三个月内没有观察到结果的显著差异,ERCP也没有对结果产生显著影响.
结论:
- 胆囊切除术和ERCP,包括联合手术,在怀孕期间是安全的干预措施.
- 该研究支持使用这些程序在孕妇患者中治疗胆结石病的可行性.
- 风险分层应考虑妊娠本身以外的因素,例如疾病的复杂性.
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