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Updated: Jul 14, 2025

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
14:55

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy

Published on: September 17, 2017

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使用X射线原子对分布函数和固态NMR探测无形药物固体的分子包装

Zhenxuan Chen1, Haichen Nie2,3, Chris J Benmore4

  • 1Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.

Molecular pharmaceutics
|October 6, 2023
PubMed
概括

对像波萨可纳这样的无形药物的高分辨率结构分析对于稳定性至关重要. 这项研究将X射线PDF和ssNMR结合起来,揭示了无形波萨可纳及其固体分散中的分子包装和相互作用.

关键词:
无形固体分散的分散.分子相互作用分子相互作用.配对分布函数的配对分布函数物理稳定性 物理稳定性固态核磁共振是一种固态核磁共振.同步子X射线X射线

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