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尖端:B细胞中的TLR2信号促进通过IL-6分泌对DNA的自主活性

Chetna Soni1, Sohei Makita1, Anna Eichinger1,2

  • 1Department of Pathology, New York University Grossman School of Medicine, New York, NY.

Journal of immunology (Baltimore, Md. : 1950)
|October 6, 2023
PubMed
概括

收费类受体2 (TLR2) 在全身性红斑狼 (SLE) 中发挥着至关重要的作用,它使B细胞能够产生抗dsDNA自身抗体. 微生物产品可能会增强SLE患者的自身免疫反应.

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