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Updated: Jul 14, 2025

Identifying Inhibitors of the HBx-DDB1 Interaction Using a Split Luciferase Assay System
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Identifying Inhibitors of the HBx-DDB1 Interaction Using a Split Luciferase Assay System

Published on: December 21, 2019

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氧化应激传感器Keap1识别HBx蛋白激活Nrf2/ARE信号通路,从而抑制乙型肝炎病毒的复制

Adi Ariffianto1,2, Lin Deng1, Takayuki Abe1

  • 1Division of Infectious Disease Control, Center for Infectious Diseases, Kobe University Graduate School of Medicine , Kobe, Japan.

Journal of virology
|October 6, 2023
PubMed
概括

由乙型肝炎病毒 (HBV) 感染激活的Nrf2/ARE通路抑制了HBV复制. 这涉及Keap1与HBx相互作用,激活Nrf2,并抑制HBV复制,这表明对HBV的治疗策略.

关键词:
在此之前,HBx HBx凯普1/Nrf2/ARE 在线观看乙型肝炎病毒的感染.

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