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Updated: Jul 14, 2025

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
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Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

Published on: April 9, 2014

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在逆转录酶抑制剂耐药性突变发生之前和之后,人体免疫缺陷病毒在血病毒中的1 5'-领导突变

Janin Nouhin1,2, Philip Lei Tzou1, Soo-Yon Rhee1

  • 1Division of Infectious Diseases, Department of Medicine, Stanford University, Stanford, CA, USA.

The Journal of general virology
|October 6, 2023
PubMed
概括

艾滋病毒-1逆转录酶 (RT) 启动涉及病毒RNA和宿主tRNA. 这项研究研究了与耐药性相关的HIV-1 5'-领导RNA和RT的共同进化变化,在特定的RNA位置发现了高突变率.

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