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过敏性结膜炎患者中食物过敏的发生率

Shaimaa H Fouad^1,2, Shereen A Baioumy³, Omar F M Zidan⁴

¹Department of Internal Medicine/Allergy and Clinical Immunology, Faculty Medicine, Ain Shams University, Cairo, Egypt.

The Egyptian journal of immunology

|October 6, 2023

概括

食物过敏与过敏性结膜炎 (AC) 有关. 语言下免疫疗法有效地降低了患者的AC严重程度和IgE水平,无论食物过敏状态如何. 这种治疗对管理AC有希望.

科学领域:

眼科医生眼科眼科
过敏学过敏学
免疫学免疫学免疫学

背景情况:

全球眼睛过敏的患病率正在上升.
食物过敏可以表现为过敏性结膜炎 (AC),但对这种联系的研究有限.
皮肤刺伤测试是诊断过敏反应中的过敏原的标准.

研究的目的:

为了调查AC患者中食物过敏的发生率.
为了确定食物过敏和AC严重程度之间的关联.
为了比较亚语言免疫疗法的有效性,在AC患者和没有食物过敏.

主要方法:

对240名AC患者进行了回顾性队列研究.
用于过敏原识别的皮肤刺伤测试.
在四个月的语言下免疫疗法之前和之后评估总血清IgE和AC严重程度.

主要成果:

食物过敏的发病率在AC患者中为29.6%,皮肤刺痛测试呈阳性.
语言下免疫疗法显著降低了总血清IgE和AC严重程度 (p<0.001).
在有或没有食物过敏的AC患者之间没有观察到治疗反应的显著差异 (p=0.63和p=1.00).

结论:

食物过敏可能会导致过敏性结膜炎的发展.
舌下过敏原免疫疗法是AC的潜在有效治疗方法.
亚舌性免疫疗法对AC的益处似乎是一致的,无论伴随性食物过敏.

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