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Updated: Jul 14, 2025

Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins
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Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins

Published on: May 22, 2017

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通过具有低质子导电性的通道罗多普辛减少神经元酸化

Rebecca Frank Hayward1, F Phil Brooks2, Shang Yang3

  • 1School of Engineering and Applied Sciences, Harvard University, Cambridge, United States.

eLife
|October 6, 2023
PubMed
概括

像CheRiff这样的高电流通道罗多普辛因质子运输而导致神经元酸化. 研究人员确定了低质子透性opsins,PsCatCh2.0和ChR2-3M,以减轻光遗传学中的这个问题.

关键词:
酸性化是指酸性化的过程.电力生理学 电力生理学分子生物物理学分子生物物理学这里是鼠标鼠标鼠标鼠标鼠标鼠标.神经科学 神经科学视觉遗传学 视觉遗传学结构生物学结构生物学

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