运动和心血管反应:设计和实施儿科CMR队列研究
Meddy N Bongers-Karmaoui1,2, Alexander Hirsch3,4, Ricardo P J Budde4
1The Generation R Study Group, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
The international journal of cardiovascular imaging
|October 6, 2023
概括
这项研究表明,同度握手运动是儿童可行的心血管磁共振 (CMR) 测试,揭示了显著的心血管反应,并提供了评估儿科心脏健康的新方法.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心血管成像 - 心血管成像
- 运动生理学 运动生理学
背景情况:
- 评估儿科心血管健康需要可靠和可复制的方法.
- 心血管磁共振 (CMR) 提供了详细的解剖学和功能性见解.
- 评估儿童对运动的心血管反应对于了解心脏功能至关重要.
研究的目的:
- 为了确定CMR期间在儿科群体中进行同度手握运动测试的可行性和可重复性.
- 评估心血管反应,包括血液动力学和体积变化,以对比手握运动在健康儿童.
- 探索基于CMR的运动测试的潜力,以检测儿科心血管健康的微妙差异.
主要方法:
- 一个由207名儿童组成的子组 (平均年龄为16岁) 来自基于人口的队列,在CMR期间进行了对称手握练习.
- 持续的心率和血压在休息和运动期间都被监测.
- CMR评估了左心室质量,大动脉张张能力,脉冲波速度,体积,射出分数,中风体积和心脏输出.
主要成果:
- 在CMR期间,对比手握练习在儿童中是可行的和可重复的.
- 在运动期间观察到心率 (42.6%) 和血压 (静缩6.4%,静缩5.4%,平均11.0%) 的显著增加.
- 左心室末/末体积和心脏输出量增加,而喷射分数略有下降 (p < 0.05).
结论:
- 在健康儿童的CMR期间,持续的同度手握运动 (7分钟在30-40%的MVC) 是可行的和有效的压力.
- 这种方法引起了显著的心血管和左心室功能变化,证明了它的实用性.
- 基于CMR的手握运动测试为儿科早期检测心血管健康差异提供了新的机会.
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