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在B2M缺陷癌症中的抗瘤免疫反应

Davis Y Torrejon1, Mildred Galvez2, Gabriel Abril-Rodriguez1,2

  • 1Department of Medicine, Division of Hematology-Oncology, University of California Los Angeles (UCLA), Los Angeles, California.

Cancer immunology research
|October 6, 2023
PubMed
概括

失去β-2微球蛋白 (B2M) 会导致对免疫检查点阻塞 (ICB) 的抵抗. 缺乏B2M的瘤仍然可以通过CD4+T细胞和NK细胞对ICB作出反应,这表明了其他免疫激活途径.

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