[家族性高胆固醇血症成年人实际营养]
A V Blokhina1, A I Ershova1, O V Kopylova1
1National Medical Research Center for Therapy and Preventive Medicine, Ministry of Health of the Russian Federation, 101990, Moscow, Russian Federation.
Voprosy pitaniia
|October 6, 2023
概括
患有家族性高胆固醇血症 (FH) 的成年人显示营养不良,超过脂肪和蛋白质摄入量,同时缺乏碳水化合物和纤维. 饮食干预对于管理这种遗传性脂质障碍至关重要.
科学领域:
- 心脏病学 心脏病学
- 营养科学 营养科学
- 遗传学 遗传学 是一个
背景情况:
- 家族性高胆固醇血症 (FH) 是一种遗传性脂质疾病,增加了动脉样硬化风险.
- 饮食修改是FH患者降脂治疗的关键组成部分.
研究的目的:
- 评估被诊断患有家族性高胆固醇血症的成人的当前营养状况.
- 为了将实际的饮食摄入量与FH管理的既定营养指南进行比较.
主要方法:
- 一项涉及100名患有可能或确定的FH的成年人的研究.
- 通过24小时的饮食回忆和与食物相关的行为问卷进行营养评估.
- 从GENMOTIV-FH研究 (临床试验:NCT04656028) 中在2019-2021年间分析的数据.
主要成果:
- 患者表现出过多的蛋白质,总脂肪,和脂肪酸和胆固醇摄入量.
- 观察到不充分的总碳水化合物和食纤维的消费.
- 每天摄入少量的蔬菜 (47.9%) 和水果 (39.1%);喜欢高脂肪的乳制品和红肉,而不是家禽和鱼.
结论:
- 患有FH的成年人的实际饮食模式与国际营养建议不一致.
- 这些发现强调了在FH患者护理中针对性饮食干预措施的关键需求.
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