低维生素B12水平可能预测缺血性中风的风险:一个横截面研究
Li Zhou1, Jiani Wang1, Mengxia Li1
1Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
低血清维生素B12水平与住院神经病患者缺血性中风风险增加有关. 补充维生素B12可能会改善这些患者的短期结果.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 研究血清维生素B12度与缺血性中风风险之间的关系.
- 专注于神经病学部门内的住院患者.
研究的目的:
- 检查血清维生素B12度与缺血性中风风险的关系.
- 评估维生素B12水平对缺血性中风的预测价值.
主要方法:
- 对2212名住院患者的横截面研究 (2020年1月至2022年1月).
- 测量了血清维生素B12,同型半氨酸和叶酸水平.
- 使用了经过调整以人口统计,生活方式和并发症因素的后勤回归分析.
主要成果:
- 43.4%的患者患有缺血性中风.
- 低维生素B12水平 (<300 pg/mL) 与缺血性中风风险有关.
- 高维生素B12水平 (≥900 pg/mL) 显示与缺血性中风的反向关联.
- 对具有良好的区分能力的维生素B12确定了316.4ppg/ml的切断值 (AUC-ROC 0.71).
结论:
- 低维生素B12水平可能成为缺血性中风的预测因素.
- 早期的维生素B12补充可以提高缺血性中风患者的短期预后.
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