在2016年至2022年期间,奥迪沙邦布巴内斯瓦尔的多结核病
Triyambakesh Mohanty1, Sujeet Kumar1, Sunil Swick Rout1
1National Reference Laboratory for TB, ICMR-Regional Medical Research Centre, Bhubaneswar, 751023, Odisha, India.
Indian journal of medical microbiology
|October 6, 2023
概括
在布巴内斯瓦尔评估了肺溢患者的结核和利法辛耐药性. 在3.8%的样本中发现了Mycobacterium tuberculosis,其中3.8%的样本表现出对利芬素的耐药性.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 胸腔溢出是结核病的一个显著的临床表现.
- 准确的诊断和药物耐药性检测对于有效的结核病管理至关重要.
研究的目的:
- 为了确定结核病的患病率和在布巴内斯瓦尔,奥迪沙州的肺部溢液患者中抗利芬辛的耐药性.
- 分析随着时间的推移和不同年龄组的结核阳性趋势.
主要方法:
- 从2016年2月到2022年12月进行了一项回顾性研究.
- 1370个多液样本使用基于弹药的核酸放大测试 (CBNAAT,Xpert MTB/RIF) 进行了测试.
- 分析了对M. tuberculosis阳性和对利芬素耐药性的数据.
主要成果:
- 3.8% (52/1370) 的腹腔液样本对M. tuberculosis.呈阳性.
- 在3.8% (2/52) 的阳性样本中检测到里芬辛耐药性.
- 结核病阳性呈现波动,在2020年达到峰值 (7.5%) 并根据年龄变化 (年龄在60岁以上的1.5%至15-30岁的6.1%).
结论:
- 在布巴内斯瓦尔,肺结核仍然是患有肺部溢液的患者的担忧.
- 这项研究强调了像CBNAAT这样的分子诊断技术对于快速检测M.结核病和抗利芬素耐药性的重要性.
- 积极性的特定年龄变化需要进一步调查和有针对性的公共卫生干预措施.
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