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MRT-ModSeq - 通过马拉松RTRT快速检测RNA修饰

Rafael de Cesaris Araujo Tavares1, Gandhar Mahadeshwar2, Han Wan3

  • 1Department of Chemistry, Yale University, New Haven, CT 06511, USA.

Journal of molecular biology
|October 6, 2023
PubMed
概括

本研究介绍了MRT-ModSeq,这是一种快速检测多个RNA修饰的方法. 它准确地绘制了RNA转录的各种化学修饰,提高了RNA研究的速度和准确性.

关键词:
史诗转录组学 史诗转录组学处理RNA处理RNA的过程二组II组逆转录酶的发生机器学习是机器学习.突变造型分析 (mutational profiling) 是一种针对突变的分析方法.

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RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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