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CD206+ M2 类巨细胞通过向 R-spondin-2 部分保护对椎间盘退化

Xiao-Chuan Li1, Wei Wang2, Cheng Jiang2

  • 1Department of Orthopedic Surgery, Gaozhou People's Hospital, No.89 XiGuan Rd, Gaozhou 525200, Guangdong, China; Central Laboratory of Orthopedics, Gaozhou People's Hospital, XiGuan Rd, Gaozhou 525200, China; Postdoctoral Innovation Practice Base of Gaozhou People's Hospital, XiGuan Rd, Gaozhou 525200, China.

Osteoarthritis and cartilage
|October 6, 2023
PubMed
概括

通过CD206识别的促进M2巨细胞,可以通过减少Rspo2.2,缓解椎间盘退化 (IDD). 骨髓细胞中的Rheb删除有助于M2巨细胞的积累,减轻IDD,并提供潜在的治疗点.

关键词:
椎间盘退化 椎间盘退化腰部疼痛 腰部疼痛 腰部疼痛在M2巨细胞中.肌肉骨疾病 肌肉骨疾病细胞核是细胞核的细胞核.一个Rspo2的两个Rspo2.

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