患有类风湿性疾病的孕妇患贫血和铁缺乏症
Ann-Christin Pecher1, Samuel Bach2, Jan Pauluschke-Fröhlich3
1Centre for Interdisciplinary Clinical Immunology, Rheumatology and Autoinflammatory Diseases, University Hospital Tübingen, Otfried-Mueller-Strasse 10, 72076 Tübingen, Germany.
Joint bone spine
|October 6, 2023
概括
患有类风湿性疾病的孕妇有较高的贫血和缺铁率,这会影响孩子的后果. 建议在这个高风险组早期补充铁.
科学领域:
- 产科和妇科 产科和妇科
- 类风湿病学 类风湿病学
- 血液学 血液学 血液学
背景情况:
- 贫血和缺铁在怀孕期间很常见,与不良结果有关.
- 患有类风湿性疾病的患者面临高血风险.
- 这项研究研究了孕妇类风湿性疾病患者的贫血和铁缺乏症.
研究的目的:
- 为了确定患有风湿性疾病的妇女在怀孕期间贫血和缺铁的患病率.
- 评估贫血是否在这个人群中构成对母亲或儿童不良结果的危险因素.
主要方法:
- 在2014-2022年期间,德国登记处 (TURIRE) 分析了368例怀孕情况.
- 贫血和铁缺乏症根据世界卫生组织标准定义.
- 关键结果包括患病率和不良事件发生率.
主要成果:
- 贫血和缺铁的患病率在整个怀孕期间增加,在第三个三个月分别达到33%和62%.
- 低血红蛋白或铁缺乏对儿童的结果产生了负面影响.
- 低血红蛋白水平矛盾地与降低母亲并发症风险有关.
结论:
- 与一般人群相比,患有风湿性疾病的孕妇患贫血和缺铁的患病率明显高.
- 这些患者往往具有先前存在的铁和血红蛋白水平损伤.
- 早期补充铁对于这个脆弱的患者群体至关重要.
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