重度巴克洛芬中毒的神经进化:从模仿脑死亡到恢复脑功能
Sebastian Berger1, Tobias Kuster2, Raoul Sutter2,3
1Intensive Care Unit, Department of Acute Medicine, University Hospital Basel, Basel, Switzerland sebastian.berger@usb.ch.
BMJ case reports
|October 6, 2023
概括
严重的巴克洛芬中毒可以模仿大脑死亡,呈现为深度昏迷和缺席脑干反射. 及时识别这种毒性病变对于患者的康复至关重要,因为症状是暂时的.
科学领域:
- 神经学 神经学
- 毒理学 毒理学 毒理学
背景情况:
- 大脑死亡是由不可逆转的脑干反射损失所定义的.
- 在确认脑死亡诊断之前,排除混因素至关重要.
- 巴克洛芬中毒是一种罕见的模仿脑死亡.
研究的目的:
- 报告一例仿真脑死亡的巴克洛芬中毒病例.
- 突出承认巴克洛芬作为潜在混剂的重要性.
主要方法:
- 一个70多岁的女性患者过量服用巴克洛芬的病例报告.
- 昏迷和脑干反射的临床评估.
- 电脑图 (EEG) 监控. 电脑图 (EEG) 监控. 电脑图 (EEG) 监控. 电脑图 (EEG) 监控.
主要成果:
- 患者呈现深度昏迷和缺席脑干反射,模仿大脑死亡.
- 脑电图显示了一个突发抑制模式,在10小时内消失.
- 患者经历了6个小时的明显脑死亡模仿后完全康复.
结论:
- 严重的巴克洛芬中毒可以呈现为暂时的脑死亡模仿.
- 在巴克洛芬中毒时的临床和EEG发现可能会被误认为是脑死亡.
- 对这种毒的认识对于适当的管理至关重要,并且可以导致完全康复.
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