玛射线杀菌对3mol%伊特里亚稳定四角形石多晶体的生物效应:一个体外研究
Le Na Lau1, Jun-Ho Cho2, Ye-Hyeon Jo3
1Graduate student, Department of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea.
The Journal of prosthetic dentistry
|October 6, 2023
概括
与相比,的马射线灭菌增加了表面粗度,并降低了细胞生物相容性. 这种方法对植入物材料不太有希望,需要进一步研究.
科学领域:
- 生物材料科学 生物材料科学
- 表面化学 表面化学
- 细胞生物学 细胞生物学
背景情况:
- 绝育方法可以改变植入物质表面化学和生物相容性.
- 关于绝育对植入物材料 (如) 的生物学影响的研究有限.
研究的目的:
- 为了评估玛射线照射3mol%的伊特里亚稳定四角形土聚晶 (3Y-TZP) 的体外生物相容性.
- 为了比较受辐射的3Y-TZP与未受辐射的,3Y-TZP和纯金的生物相容性.
主要方法:
- 准备的,3Y-TZP,玛辐射3Y-TZP和黄金的磁盘样本.
- 使用MC3T3-E1细胞评估骨质生成潜力.
- 通过SEM,CLSM和EDS检查了表面地形,化学和细胞形态.
主要成果:
- 与和黄金相比,玛射线灭菌增加了3Y-TZP表面粗度.
- 被辐射的3Y-TZP显示出比黄金更高的初始细胞增殖和粘附,但比更低的细胞扩散.
- 在第3天,照射3Y-TZP的细胞增殖率低于未照射3Y-TZP.
结论:
- 与和相比,玛辐射石表现出表面粗度增加和生物活性显著降低.
- 在生物相容性方面,马射线灭菌不是一种有希望的石方法.
- 需要进一步研究对植入物材料的灭菌效应.
相关概念视频
Methods of Sterilization I: Physical Methods
20.1K
As used in a healthcare facility, sterilization destroys all microorganisms through physical or chemical methods. The physical method includes steam, dry heat, boiling water, and radiation.
Steam sterilization uses non-toxic, low-cost moist heat in the form of saturated steam under pressure, which is fast, microbicidal, and sporicidal, and quickly warms and penetrates fabrics. Autoclaves, or steam sterilizers, expose each item to direct steam contact for a predetermined time at the necessary...
Steam sterilization uses non-toxic, low-cost moist heat in the form of saturated steam under pressure, which is fast, microbicidal, and sporicidal, and quickly warms and penetrates fabrics. Autoclaves, or steam sterilizers, expose each item to direct steam contact for a predetermined time at the necessary...
20.1K
Methods of Sterilization II: Chemical Methods
6.5K
In healthcare, the chemical method of sterilization uses chemical sterilants to treat surgical instruments and medical supplies to help prevent the transmission of infectious pathogens to patients. Due to heat sensitivity, most medical supplies and equipment should not be exposed to high temperatures. These parts include rubber, plastic, glass, and other similar elements.
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
6.5K
Biological Effects of Radiation
15.5K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
15.5K


