[建立基于最佳临床经验的临床疗效评估系统]
Zhong-Qi Yang1, Ya-Qin Tang1, Hui-Min Tang1
1the First Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou 510405, China.
概括
由于临床试验的局限性,传统中医 (TCM) 面临整合基于证据的医学 (EBM) 的挑战. 一种新的方法",基于临床综合征的医学",利用最佳的临床经验来增强TCM.
科学领域:
- 综合医学是一个整体医学.
- 传统中国医学 (TCM) 是一种
- 基于证据的医学 (EBM)
背景情况:
- 基于证据的医学 (EBM) 对临床决策至关重要,但研究证据可能不适用于个人患者.
- 20年来,EBM融入中国传统医学 (TCM) 取得了有限的成功,EBM开发的TCM指南的接受度很低.
- 在TCM的临床实践特征和传统的临床随机对照试验 (RCT) 之间存在结构性矛盾,阻碍了准确的疗效和安全性反射.
研究的目的:
- 为了解决将EBM应用于TCM的局限性.
- 提出一个新的框架",基于临床综合征的医学",与TCM独特的临床实践保持一致.
- 在EBM背景下加强TCM的临床疗效和安全性评估.
主要方法:
- 分析将EBM原则和RCT应用于TCM的挑战.
- 基于最佳临床经验的"基于临床综合征的药物"的建议.
- 推现实研究方法,以确定临床经验中的规律性和可重复性.
主要成果:
- 确定TCM中传统的RCT可能会损害其核心优势,如综合征差异化和适应性处方.
- 提出"基于临床综合征的医学",作为一种将TCM的临床特征与EBM概念相结合的方法.
- 突出最佳的临床经验,以规律性和可重复性为特征,作为新方法的关键.
结论:
- 基于临床综合征的医学为TCM研究提供了一个范式转变,尊重其整体方法.
- 这种综合方法旨在提高TCM证据的可靠性和适用性.
- 该框架有助于更好地将TCM纳入基于证据的医疗保健的更广泛的格局.
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