在有癌症和没有癌症的老年人中,新的和持续的阿片类药物使用趋势
Laura Van Metre Baum1,2, Madhav Kc2, Pamela R Soulos2
1Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Journal of the National Cancer Institute
|October 6, 2023
概括
癌症患者的阿片类药物处方下降速度比其他患者慢. 虽然新的阿片类药物使用减少了,但早期的额外使用出现了各种变化,这表明阿片类药物减少努力对癌症患者的影响有所缓和.
科学领域:
- 在瘤学瘤学.
- 疼痛管理 疼痛管理
- 公共卫生 公共卫生
背景情况:
- 目前正在进行的阿片类药物减少工作对癌症患者的影响尚不清楚.
- 需要了解癌症患者与普通人群使用阿片类药物的趋势.
研究的目的:
- 在患有癌症和没有癌症的患者中确定新的和额外的阿片类药物使用趋势.
- 比较2012-2017年癌症患者和非癌症患者之间的阿片类药物使用模式.
主要方法:
- 使用监测,流行病学和最终结果 (SEER) -医疗保险数据的回顾性队列研究.
- 包括2012-2017年诊断的固体瘤的阿片类药物原始患者和没有癌症的对照组.
- 在四个层面分析了新的,早期的额外和长期的额外阿片类药物使用:没有癌症,转移性癌症,单独的手术和手术+.
主要成果:
- 癌症患者 (46.4%) 的新阿片类药物使用明显高于非癌症患者 (6.9%).
- 与非癌症患者 (20.0%) 相比,癌症患者 (0.1%-8.8%) 的新阿片类药物使用下降速度更慢.
- 早期额外的阿片类药物使用在手术患者中下降,但在转移性癌症患者中保持稳定.
结论:
- 与没有癌症的患者相比,癌症患者的阿片类药物处方减少的速度较慢.
- 变化的阿片类药物气候对癌症患者产生了重要但有限的影响.
- 需要进一步的研究,以优化癌症患者的疼痛管理策略,在阿片类药物减少计划中.
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