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Updated: Aug 3, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
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Published on: May 6, 2010

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MetaCC允许对长读和短读元基因组 Hi-C 数据进行可扩展和整合分析

Yuxuan Du1, Fengzhu Sun2

  • 1Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, USA.

Nature communications
|October 6, 2023
PubMed
概括

MetaCC是一个新的框架,用于分析从短读和长读的元基因学Hi-C (metaHi-C) 数据. 它提供更快的正常化和改进的基因组组分,显著推进微生物社区分析.

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RNA-seq03:21

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...