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Updated: Jul 14, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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开发PI3Kγ选择性抑制剂:战略和应用

Dong-Yan Gu1, Meng-Meng Zhang2, Jia Li2

  • 1College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.

Acta pharmacologica Sinica
|October 6, 2023
PubMed
概括

选择性酸胺3-激酶 (PI3Kγ) 抑制剂对于治疗炎症和自身免疫性疾病至关重要. 本综述详细介绍了开发PI3Kγ选择性抑制剂的策略,以尽量减少不良事件.

关键词:
在PI3K中,PI3K是指PI3K.的PI3Kγ抑制剂.药物开发是药物的发展.异形选择性是异形选择性的.有理性的药物设计.

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