牙周炎与中风相关
Xiaodan Zheng1,2, Xin Li3,4, Juanying Zhen1,5
1Department of Neurology, Peking University Shenzhen Hospital, 1120 Lianhua Rd, Futian District, Shenzhen, 518036, Guangdong, China.
Journal of translational medicine
|October 6, 2023
概括
牙周炎是一种牙疾病,与中风风险增加有关. 严重的牙周炎几乎使中风风险增加了三倍,而中度的牙周炎则增加了71%.
科学领域:
- 口腔健康 口腔健康
- 神经学 神经学
- 心血管健康 心血管健康
背景情况:
- 牙周炎是心血管疾病和动脉样硬化的已知危险因素.
- 牙周炎和中风之间的具体联系尚未得到充分研究.
- 这项研究调查了牙周炎和中风发病率之间的关联.
研究的目的:
- 探索牙周炎和中风之间的关系.
- 为了确定牙周炎是否会增加中风风险.
- 量化牙周炎和中风不同严重程度之间的关联.
主要方法:
- 利用了来自国家健康和营养检查调查 (2009-2014) 的6460名参与者的数据 (代表超过9200万美国成年人).
- 采用精确的临床附着水平和探针口袋深度测量来诊断牙周炎.
- 使用复杂的抽样设计进行统计分析,以考虑调查的方法.
主要成果:
- 39.9%的参与者患有牙周炎; 2.1%的人被诊断为中风.
- 脑卒中风险与牙周炎的严重程度显著相关 (p为趋势=0.018).
- 严重牙周炎增加了中风的几率2.55倍 (OR:2.55,95% CI:1.25-5.21),中度牙周炎增加了1.71倍 (OR:1.71,95% CI:1.17-2.50),即使经过多种风险因素的调整.
结论:
- 在美国成年人中,牙周炎和中风之间存在显著的关联.
- 严重和中度牙周炎与大幅增加中风风险有关.
- 改善牙健康管理可能有助于预防中风的策略.
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