纤维肌痛患者的听力损失和影响因素
Hanife Caglar Yagci1, Osman Ilkay Ozdamar2, Ozlem Ertugrul3
1Department of Physical Medicine and Rehabilitation, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkey.
概括
新确诊的纤维肌痛患者表现出高率的感觉神经神经听力损失,特别是影响更高频率. 这项研究调查了与健康对照组相比,纤维肌痛患者的听力障碍.
科学领域:
- 听力学 听力学是指听力学.
- 类风湿病学 类风湿病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 纤维肌痛综合征 (FM) 是一种慢性疾病,其特点是广泛的疼痛和高度敏感.
- 听力损失是慢性炎症和自身免疫疾病患者的新兴问题.
- 中央敏感性在FM病理生理学中起着关键作用.
研究的目的:
- 确定新诊断为纤维肌痛的患者中听力损失的患病率.
- 在这个人群中确定与听力损失相关的因素.
主要方法:
- 一项描述性研究,将33名新诊断的纤维肌痛患者与32名年龄和性别匹配的健康对照人进行比较.
- 听力学评估包括纯色音量计 (PTA) 和短暂唤起的耳声发射 (TEOE).
- 患者填写了关于非类固醇抗炎药物 (NSAID) 使用和纤维肌痛影响 (ASAS-NSAID评分) 的标准化问卷.
主要成果:
- 与对照组相比,纤维肌痛患者的主观耳 (12%),头 (18%) 和听力损失 (15%) 的发生率明显高.
- 纯色音频测试显示了两组之间的显著差异,在更高频率时异常更明显.
- 在纤维肌痛患者中,过渡唤起的耳声发射在3000Hz和4000Hz (p<0.05) 时显示得分明显较低.
结论:
- 刚被诊断为纤维肌痛的患者有很高的感觉神经听力损失发病率.
- FM患者的听力测量异常在高频率中更为突出,但也会影响低频率.
- 纤维肌痛中的听力损失可能与中心敏感化和耳毒性影响有关.
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