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相关概念视频

Stem Cell Therapy for Tissue Regeneration01:21

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
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Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
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基于MXene的多功能生物活性材料用于综合再生疗法.

Junping Ma1, Long Zhang1,2, Bo Lei1,3

  • 1Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710000, China.

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|October 7, 2023
PubMed
概括

先进的纳米材料MXenes在组织再生和疾病治疗方面表现有前途. 本综述探讨了它们在治疗癌症,感染和炎症的综合再生疗法中的应用,强调了潜力和挑战.

关键词:
这就是MXenesenes.生物活性材料是生物活性材料.骨再生 骨的再生癌症治疗疗法 癌症治疗感染治疗的治疗方法.炎症治疗疗法 炎症治疗具有多功能性质的特性.组织工程是组织工程.伤口愈合 伤口愈合

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科学领域:

  • 生物医学工程 生物医学工程
  • 材料科学 材料科学 材料科学
  • 纳米技术纳米技术

背景情况:

  • 来自癌症,感染和炎症等疾病的组织缺陷带来临床挑战.
  • 多功能生物活性材料对于克服受损组织再生至关重要.
  • 作为二维纳米材料的MXenes为生物医学应用提供了独特的特性.

研究的目的:

  • 审查MXene特性及其在综合组织再生和治疗中的应用方面的最新进展.
  • 探索基于MXene的生物材料,用于结合组织再生与瘤,感染和炎症治疗.
  • 讨论基于MXene的再生疗法的当前挑战和未来前景.

主要方法:

  • 关于MXene特性和在组织工程和治疗中的应用的文献综述.
  • 基于MXene的生物材料用于联合再生治疗策略的分析.
  • 讨论MXenes的机制,生物安全性和准能力.

主要成果:

  • MXenes具有适用于纳米平台的多功能物理化学特性.
  • 基于MXene的生物材料显示出结合癌症,感染和炎症治疗的组织再生潜力.
  • 应用包括光热疗法,细胞行为调节和药物/基因输送.

结论:

  • 基于MXene的生物材料对综合组织再生和疾病治疗具有重大前景.
  • 需要进一步的研究来了解生物活性机制,并确保长期的生物安全性.
  • 提高向治疗能力对于MXene应用的临床转化至关重要.