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Updated: Aug 2, 2026

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
07:53

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation

Published on: January 9, 2019

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重新利用Navitoclax来阻止SARS-CoV-2的融合和进入,通过准S2蛋白中的七倍重复序列1来阻止

Fanke Jiao1, Alexander M Andrianov2, Lijue Wang1

  • 1Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microbes and Infection, Fudan University, Shanghai, China.

Journal of medical virology
|October 7, 2023
PubMed
概括

现有的癌症药物Navitoclax通过阻止病毒融合,有效抑制SARS-CoV-2变种和其他冠状病毒. 这种重新设计的药物显示出作为口服可用的,广泛的抗病毒治疗的前景.

关键词:
在Navitoclaxx上使用.这就是SARS-CoV-2病毒.广泛的频谱使用.人类新冠肺炎病毒一个六螺旋捆绑.小分子抑制剂小分子抑制剂

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Engineering Antiviral Agents via Surface Plasmon Resonance13:00

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