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相关概念视频

Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

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Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
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What is Genetic Engineering?00:49

What is Genetic Engineering?

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Overview
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Epigenetic Regulation01:37

Epigenetic Regulation

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Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
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CRISPR01:59

CRISPR

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Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
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Human Genetics01:28

Human Genetics

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Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
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Inheritance of Chromatin Structures03:17

Inheritance of Chromatin Structures

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Epigenetics is the study of inherited changes in a cell's phenotype without changing the DNA sequences. It provides a form of memory for the differential gene expression pattern to maintain cell lineage, position-effect variegation, dosage compensation, and maintenance of chromatin structures such as telomeres and centromeres. For example, the structure and location of the centromere on chromosomes are epigenetically inherited. Its functionality is not dictated or ensured by the underlying...
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相关实验视频

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Author Spotlight: RNAi Inheritance and ChIP in C. elegans
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Author Spotlight: RNAi Inheritance and ChIP in C. elegans

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[跨代表观遗传学及其生物伦理影响]

Nicolás Jouve de la Barreda1

  • 1Departamento de Biotecnología y Biomedicina, Universidad de Alcalá, Alcalá de Henares (Madrid), España. nicolas.jouve@uah.es.

Cuadernos de bioetica : revista oficial de la Asociacion Espanola de Bioetica y Etica Medica
|October 7, 2023
PubMed
概括

表观遗传修饰影响基因表达而不改变DNA序列. 虽然通常不会传给后代,但它们会影响健康,在动物中,跨代遗传仍未得到证实.

科学领域:

  • 表观遗传学:研究基因表达修饰而不改变DNA序列.
  • 专注于调节基因活动和沉默的表观遗传机制在更高的动物.

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