自然 (几乎) 总是占上风 - - 挑战人工循环冷胚胎转移现状
Samuel Santos-Ribeiro1, Catarina M Godinho2, Sérgio Reis-Soares2
1IVIRMA Global Research Alliance, IVIRMA Lisboa, Lisbon, Portugal.; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Lisbon, Lisbon, Portugal..
Reproductive biomedicine online
|October 7, 2023
概括
冷胚胎移植 (FET) 在辅助生殖技术中很常见. 优化自然循环FET协议是改善患者便利和妊娠结果的关键,平衡有效性与减少监测需求.
科学领域:
- 生殖医学 生殖医学
- 妇科 妇科 妇科 妇科
- 内分泌学 在内分泌学.
背景情况:
- 冷胚胎移植 (FET) 越来越多地被用于辅助生殖技术 (ART),遵循"结所有"策略和改进的冷保存.
- 人工和自然周期之间的选择对于FET准备是有争议的,影响子宫内膜受容性,计划和怀孕结果.
- 人工循环提供了灵活性,但可能会增加流产和高血压疾病的风险,而自然循环需要密集监测.
研究的目的:
- 评估提高自然循环FET的实用性和利用的战略.
- 探索新的方法,以改善患者的便利性和FET准备的结果.
- 解决与自然周期监测和无排卵相关的挑战.
主要方法:
- 关于人工与自然循环FET协议的现有文献的审查.
- 对优化自然循环FET的建议策略的分析,包括对无排卵的最小刺激和对人类胆管性腺激素 (hCG) 给药的新时间.
- 探索自然增殖阶段协议及其潜在益处.
主要成果:
- 人工循环提供了方便,但潜在的风险,如更高的流产率.
- 自然循环需要频繁的监测,这带来了调度挑战.
- 新的FET方法,包括调整的hCG时间和自然增殖阶段协议,有望改善结果和方便性.
结论:
- 提高自然循环FET的实用性对于更广泛的ART应用至关重要.
- 需要进一步的研究来确定新型FET策略的最佳时间和有效性.
- 平衡监测需求与患者方便是自然循环FET成功的关键.
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