复发性结合组织疾病相关组织性肺炎的临床特征
Junji Otsuka1, Shigeru Yoshizawa2, Kunihiro Kudo3
1Department of Respiratory Medicine, National Hospital Organization Fukuoka National Hospital, 4-39-1 Yakatabaru, Minami-ku, Fukuoka City, Fukuoka, 811-1394, Japan; Department of Respiratory Medicine, National Hospital Organization Omuta National Hospital, 1044-1, Tachibana, Omuta City, Fukuoka, 837-0911, Japan.
Respiratory medicine
|October 7, 2023
概括
结合组织疾病相关组织性肺炎 (CTD-OP) 患者在诊断时未接受CTD治疗,以及在使用类固醇后实现部分缓解的患者,复发风险更高. 密切监测CTD发病在复发病例中至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 组织性肺炎 (OP) 是一种非特定的肺损伤反应.
- 皮质类固醇是有效的,但复发是常见的,特别是当减少治疗时.
- 与结合组织疾病相关的OP (CTD-OP) 中复发的风险因素尚不清楚.
研究的目的:
- 为了调查CTD-OP患者复发的频率.
- 确定与CTD-OP.中复发相关的临床特征和风险因素.
主要方法:
- 对47名CTD-OP患者的数据进行了回顾性审查.
- 在CTD-OP患者与没有复发之间的临床数据的比较.
- 多变量分析以确定复发的独立风险因素.
主要成果:
- 23.4%的CTD-OP患者经历了复发.
- 复发的独立风险因素包括在OP诊断时没有CTD治疗和在类固醇治疗后的部分缓解.
- 在类风湿性关节炎相关的OP (RA-OP) 中,部分缓解和诊断时的年龄较小是危险因素.
结论:
- 在CTD-OP患者中,在HRCT和之前的OP诊断上有残留疾病的患者更容易复发.
- 在复发性OP患者中,早期CTD诊断很重要.
- 在复发性OP患者的临床过程中,对CTD发病的监测至关重要.
相关概念视频
COPD: Pathogenesis and Clinical Features
317
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
317
Pneumonia II: Pathophysiology
300
The pathophysiology of pneumonia involves the following steps:
300
Pneumonia III: Complications and Assessment
245
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
245
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.8K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.8K
Pneumonia I: Introduction
254
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
254
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.8K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.8K


