在自然衰老小鼠的心脏中,蛋白质组学和β-基基化修饰特性

Xuechun Yang1, Xuehui Li1, Na Yu2

  • 1Department of Geriatric Medicine, Key Laboratory of Cardiovascular Proteomics of Shandong Province, Qilu Hospital of Shandong University, Jinan, Shandong, China.

概括

老化的心脏表现出改变的氨酸β-氧基化 (Kbhb) 模式,特别是在线粒体能量代谢蛋白中. 这项研究揭示了Kbhb作为与年龄有关的心血管疾病的潜在治疗点.

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