肺部移植后发现肺部疾病的意想不到原因
Alyssa Self1, Kamyar Afshar1, Aarya Kafi1
1Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California San Diego, San Diego, CA.
Chest
|October 7, 2023
概括
本案例研究讨论了一名54岁的女性,患有全身性红斑狼和间歇性肺病 (ILD),由于症状进展,尽管进行了最大限度的医疗治疗,但被评估为肺移植.
科学领域:
- 肺部病理学 肺部病理学
- 类风湿病学 类风湿病学
- 移植手术 移植手术
背景情况:
- 系统性红斑狼 (SLE) 可以表现为严重的肺部并发症,包括间歇性肺病 (ILD) 和肺动脉高血压 (PAH).
- 这个案例突出了一个患有已确定的SLE-ILD和PAH的患者,不耐医疗治疗.
- 考虑了SLE患者ILD的诊断方法,特别是肺活检的作用.
研究的目的:
- 提出一个复杂的病例,一个患有SLE-ILD和PAH的患者被评估为肺移植.
- 讨论这些患者所需的管理挑战和多学科方法.
主要方法:
- 54岁女性患有SLE,ILD和PAH的临床病例介绍.
- 审查她的病史,诊断工作 (临床和放射特征),以及当前的药物治疗.
- 对肺移植候选人的评估.
主要成果:
- 患者呈现出进展性呼吸道症状,尽管接受了氧化,美酸莫菲蒂尔,尼丁达尼布,吸入式特雷普罗斯,西尔代纳菲尔和马西坦坦的治疗.
- 由于疾病的严重程度和进展,她被认为是肺移植评估的候选人.
结论:
- 肺移植是选择高级SLE-ILD和不响应医疗治疗的PAH患者的潜在治疗选择.
- 多学科评估对于管理自身免疫性肺部疾病的复杂病例至关重要.
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