乳腺癌II-III期的新辅助化疗:一个单中心的经验
Haidi Abd El Zaher1, Hamada Fathy1, Mohamed Abozeid2
1Surgical Oncology Unit, Department of Surgery, Faculty of Medicine, Suez Canal University Hospital, Ismailia, Egypt.
World journal of surgical oncology
|October 7, 2023
概括
新辅助性全身化疗 (NAC) 在可手术的乳腺癌患者中显著增加了乳腺保护手术 (BCS) 的资格. 这种方法对于管理II-III阶段的乳腺癌至关重要,改善了手术选择.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 医学瘤学 医学瘤学
背景情况:
- 新辅助性全身化疗 (NAC) 是可手术乳腺癌的关键治疗方式.
- 评估其对手术资格的影响对于治疗规划至关重要.
研究的目的:
- 评价NAC在增加可手术的乳腺癌II-III期妇女的乳腺保护手术 (BCS) 资格方面的作用.
- 确定在NAC后成为BCS候选人的患者比例.
主要方法:
- 对147名患有可手术,II-III期乳腺癌的妇女进行了回顾性图表审查,这些妇女计划参加NAC.
- 在NAC之前和之后的BCS资格变化的分析.
- 评估与BCS资格和结果相关的因素.
主要成果:
- 在NAC之前,44.9%的患者有资格接受BCS.
- 在NAC之后,另外49.4%以前不符合条件的患者成为合格的患者.
- 获得BCS的资格与年轻的年龄和雌激素受体消极性显著相关.
结论:
- 美国乳腺癌协会 (NAC) 在提高可手术,II-III期乳腺癌妇女的BCS资格方面发挥着至关重要的作用.
- 这种新辅助方法扩大了手术选择,并有可能改善患者的治疗结果.
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