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Updated: Jul 14, 2025

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
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集成蛋白信号传递对于T细胞急性淋巴细胞白血病的骨髓介导支持至关重要

Aram Lyu1, Ryan S Humphrey1, Seo Hee Nam1

  • 1Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.

Nature communications
|October 7, 2023
PubMed
概括

T细胞急性淋巴细胞白血病 (T-ALL) 细胞需要与髓质细胞密切接触才能生存. 通过FAK/PYK2传递因特格林驱动的信号对于这种髓状细胞的支持至关重要,影响白血病的进展和患者的预后.

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