非同名突变对SARS-CoV-2 NSP3和NSP4基因内的miRNA结合部位的影响

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Updated: Jul 14, 2025

MicroRNA-based Regulation of Picornavirus Tropism
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MicroRNA-based Regulation of Picornavirus Tropism

Published on: February 6, 2017

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S M Ali Hosseini Rad1,2,3, Dhammika Leshan Wannigama4,5,6,7,8,9,10, Nattiya Hirankarn11,12

  • 1Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand. a.hoseini.rad@gmail.com.

Scientific reports
|October 7, 2023
PubMed
概括

在SARS-CoV-2 (严重急性呼吸系统综合征冠状病毒2) 变异中出现的反复突变可以破坏微RNA结合部位,可能影响病毒健康和复制. 这项研究证实了microRNA与病毒区域的结合,并显示由于特定突变而减少结合.

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