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[共同表达IL-15和CCL19的EGFRvIIICAR-T细胞的结构和功能分析]

Wanqiong Chen1, Na Xian2, Shaomei Lin1

  • 1School of Pharmacy, Quanzhou Medical College, Quanzhou 362011, Fujian, China.

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
|October 8, 2023
PubMed
概括

针对EGFRvIII的工程CAR-T细胞显示出增强的增殖,化疗和抗亡能力. 这些修改后的细胞共同表达介素-15和化学酶CCL19,有望改善质母细胞瘤治疗.

关键词:
C-C 化学因子连接体 19 连接体仿真抗原受体T细胞的T细胞受体质母细胞瘤 (glioblastoma) 是一种介质蛋白-15 介质蛋白-15皮肤外皮生长因子受体的III类变体.

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