在儿童痴呆症疾病中表征常见的现象:来自澳大利亚两个中心的横截面研究
Jason V Djafar1, Nicholas J Smith2, Alexandra M Johnson3
1Discipline of Paediatrics and Child Health, School of Clinical Medicine, UNSW Medicine and Health, Sydney, Australia.
Pediatric neurology
|October 8, 2023
概括
儿童痴呆症有共同的症状,如沟通,睡眠和移动性问题,严重影响家庭. 认识到这些统一的特征可以改善对这些罕见的儿科疾病的护理和研究.
科学领域:
- 儿科神经学 儿科神经学
- 神经发育障碍 神经发育障碍
- 罕见疾病 罕见疾病
背景情况:
- 儿童痴呆症是一种罕见的儿科疾病,导致神经认知能力逐渐下降.
- 了解共享的表型对于优化护理和推进研究至关重要.
研究的目的:
- 描述患有痴呆症综合征的儿童的表型.
- 为了确定不同儿童痴呆症状况之间的共同点.
主要方法:
- 在澳大利亚对45名患有23种痴呆症候群的儿童进行了横截面研究.
- 使用经过验证的工具评估行为,饮食,睡眠,疼痛和神经障碍.
- 收集的社会人口统计和临床数据的描述性统计分析.
主要成果:
- 82%的儿童有中度至严重的神经障碍和功能依赖.
- 普遍存在的表型包括沟通 (87%),睡眠障碍 (80%),食欲变化 (74%).
- 行为问题显著影响家庭生活 (73%).
结论:
- 儿童痴呆症疾病表现出共同的行为,运动和社会情绪症状,尽管异质.
- 这些疾病的集体术语可以提高治疗,护理质量和加速研究.
- 高关怀需求与这些共同的症状有关.
更多相关视频
11:29Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools
Published on: June 20, 2020
9.1K
06:46Automated, Long-term Behavioral Assay for Cognitive Functions in Multiple Genetic Models of Alzheimer's Disease, Using IntelliCage
Published on: August 4, 2018
12.2K
相关概念视频
01:30Dementia
124
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
124
01:19Autism Spectrum Disorder
119
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
119
01:26Alzheimer's Disease: Overview
506
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
506
01:30Attention-Deficit/Hyperactivity Disorder
79
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
79
01:30Oppositional Defiant Disorder
32
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Diagnostic Criteria and...
32
01:35Pedigree Analysis
84.4K
Overview
84.4K