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Updated: Jul 14, 2025

Evaluating In Vitro DNA Damage Using Comet Assay
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奥拉巴里布的药理动力学提升:一个随机交叉研究 (PROACTIVE-研究)

Joanneke K Overbeek1, Niels A D Guchelaar2, Ma Ida Mohmaed Ali3

  • 1Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, Gelderland, the Netherlands.

European journal of cancer (Oxford, England : 1990)
|October 8, 2023
PubMed
概括

与cobicistat一起提高olaparib的药理动力学提升增加了药物暴露,但没有达到剂量等效. 需要进一步的研究来证实强化olaparib治疗的耐受性.

关键词:
在 CYP3A4 中.科比西斯塔特 (Cobicistat) 是一种制剂.这就是Olaparib.药物增强的药物增强药物动力学提升 药物动力学提升

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