目前对神经血管与年龄相关的黄斑退化症中亚视网膜出血的管理
Damla Oncel1, Deniz Oncel1, Kapil Mishra2
1Loyola University Chicago Stritch School of Medicine, Chicago, Illinois, USA.
概括
在与年龄相关的黄斑变性 (AMD) 中,视网下出血 (SRH) 可能导致视力丧失. 本综述探讨了SRH目前的手术和非手术治疗方法,考虑到出血大小.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 斑点退化症 斑点退化症
背景情况:
- 与年龄相关的黄斑变性 (AMD) 是老年人不可逆转的视力丧失的主要原因.
- 亚视网膜出血 (SRH) 影响大约12%的AMD患者,对视力构成重大威胁.
- SRH的并发症包括铁毒性,营养缺乏和光受体损伤,导致斑点痕.
研究的目的:
- 审查与年龄相关的黄斑退行症 (AMD) 患者的上性出血 (SRH) 目前的手术和非手术治疗策略.
- 分析各种治疗方法的配套文献.
- 突出针对不同大小的SRH量身定制的治疗方式.
主要方法:
- 关于在AMD中治疗SRH的现有文献的综述.
- 对手术干预的分析,包括帕斯普拉纳视切除术 (PPV) 和辅助手术.
- 评估非手术选择,如静脉内注射和光动力学疗法.
主要成果:
- 存在多种手术技术,通常涉及PPV与动作相结合,如出血排水,tPA注射和抗VEGF治疗.
- 非手术选择包括内抗VEGF单疗法,没有PPV的tPA和光动力学疗法.
- 治疗选择可能会根据子皮质血流的大小而有所不同.
结论:
- 目前在AMD中的SRH管理缺乏标准化的协议.
- 使用了手术和非手术方法的组合.
- 根据SRH大小量身定制治疗对于优化视觉结果至关重要.
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