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Updated: Jul 14, 2025

In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox
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使用基于生理学的动力学建模预测急性帕拉克瓦特毒性,其中包括通过OCT2载体体在体外活性脏分泌

Annelies Noorlander1, Sebastiaan Wesseling1, Ivonne M C M Rietjens1

  • 1Division of Toxicology, Wageningen University, Stippeneng 4, 6708 WE Wageningen, the Netherlands.

Toxicology letters
|October 8, 2023
PubMed
概括

这项研究开发了一种使用生理学基础的动力学 (PBK) 模型来预测 (PQ) 毒性的新方法. 包括脏分泌改善了预测,在毒性评估中显示出新方法方法 (NAM) 的前景.

关键词:
主动脏分泌活动.有急性毒性的急性毒性.新方法方法论 (NAM)帕拉克瓦特 (Paraquat) 是一种类型.基于生理学的动力学 (PBK) 建模.量化体外-体外抽取 (QIVIVE) 的方法扩展因子的扩展因子

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Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures10:44

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