在结石疾病中的比较有效性研究的系统范围审查
Pankaj Dangle1, Gregory E Tasian2, David I Chu3
1Division of Pediatric Urology, Riley Hopsital for Children at IU Health, Indianapolis, IN.
Urology
|October 8, 2023
概括
对结石的比较有效性研究主要集中在手术干预和医疗驱逐疗法 (MET) 上. 虽然高质量的研究正在增加,但以患者为中心的结果需要在结石研究中得到更广泛的整合.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医疗保健服务研究 医疗服务研究
背景情况:
- 石疾病需要有效的预防和治疗策略.
- 对比疗效研究 (CER) 对于指导治疗结石的临床决策至关重要.
- 了解结石CER的趋势,可以为未来的研究重点提供信息.
研究的目的:
- 系统地审查对结石疾病的比较有效性研究的情况.
- 分析研究结果,方法,人群,时间趋势和以患者为中心的方法.
- 为了确定当前结石CER的差距和机会.
主要方法:
- 2005年1月至2021年3月发表的文章的系统范围审查.
- 包括英语研究,比较两种或多种干预措施,以预防结石,诊断,治疗,监测或护理.
- 独立审稿人提取数据,并使用线性回归分析描述性统计数据和时间趋势.
主要成果:
- 手术干预和医疗驱逐疗法 (MET) 是最受研究的主题.
- 随机对照试验在大多数类别中普遍存在.
- 患者报告的结果在MET和止痛药研究中经常被使用,但在其他研究中使用率较低.
- 随着时间的推移,元分析和多中心研究显著增加.
结论:
- 关于结石的比较文献主要由手术和MET研究主导.
- 患者报告结果的使用存在显著差异,特别是在手术研究中.
- 虽然更高层次的证据和多中心研究越来越多,但需要在结石疾病中进行更多的协作,高质量和以患者为中心的研究.
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