患有食后应急综合征的患者对胃部的感知功能有问题,但他们的心跳感知正常:一项病例对照研究
Kohei Yoshida1, Tetsuya Abe2, Kenji Kanbara2,3
1Department of Psychosomatic and General Internal Medicine, Kansai Medical University, 2-5-1-505 Shinmachi, Hirakata, 573-1010, Osaka, Japan. k.yoshida4104@gmail.com.
BioPsychoSocial medicine
|October 8, 2023
概括
患有食后应急综合征的患者表现出胃内接收受损,水负荷测试容量减少但心脏感知正常. 这表明胃部局部的内脏过敏,而不是一般的.
科学领域:
- 胃肠病学 胃肠病学
- 神经科学是一个神经科学.
- 心理生理学 心理生理学
背景情况:
- 功能性消化不良的特点是内脏过敏,可以局部或广泛,缺乏简单的评估方法.
- 评估身体不同部位的整体感知精度有助于评估对刺激的感知过敏性.
- 这项研究通过比较患有食后应急综合征 (PDS) 和健康对照患者的胃和心脏感官感知来研究内脏过敏症.
研究的目的:
- 在患有PDS的患者中表征内脏过敏.
- 为了比较PDS患者和健康志愿者之间的胃感官感知 (水负荷测试) 和心脏感知 (心跳跟踪任务).
- 探索胃和心脏整体感应与心理测量之间的关系.
主要方法:
- 16名PDS患者和16名健康的女性志愿者进行了长达6小时的禁食.
- 参与者填写了关于生活质量,抑郁,焦虑,亚历克西西米亚和体感放大问题的问卷.
- 用五分钟的水负荷测试来评估胃感官感知,并通过心跳跟踪任务来评估心脏感知.
主要成果:
- 与健康志愿者 (644.1毫升) 相比,PDS患者的饮用能力 (360.9毫升) 显著降低 (P=.009).
- 在PDS患者 (0.599) 和健康志愿者 (0.623) (P=.647) 之间,心跳感知得分没有显著差异.
- 在健康志愿者中,饮酒能力和心跳感知之间存在负相关性,但在PDS患者中没有,这表明PDS患者失去了心脏-胃感知关系.
结论:
- 患有PDS的患者表现出胃感觉感知 (水负荷测试) 降低,但心脏感知正常,表明局部胃过敏.
- 在PDS患者的胃和心脏整体感受之间的分离突出显示了胃整体感受功能的潜在损害.
- 在多个部位同时进行感官检查可能有价值,以区分局部和广泛的内脏过敏.
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