[用女性间歇性囊炎的化-水分阻塞治疗静脉内灌注的治疗]

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Peng Xin¹, Hao Zhang¹, Zhen Ming Jiang¹

¹Department of Urology, The First Hospital of China Medical University, Shenyang 110001, China.

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

|October 9, 2023

概括

这项研究表明,静脉内肝素/化利多卡因与水分扩张和通过尿道充血有效治疗间歇性囊炎 (IC). 这种组合疗法显著改善了患者的症状和膀功能,为IC患者提供了有前途的治疗选择.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
胃肠病学胃肠病学
药理学药理学是指药理学的学科.

背景情况:

间歇性囊炎 (IC) 是一种慢性疾病,其特征是膀疼痛和尿急.
目前IC的治疗选择具有不同的疗效和潜在的副作用.
研究新的治疗方法对于改善患者在IC管理中的结果至关重要.

研究的目的:

为了评估静脉肝素/化利多卡因与水分扩张和通过尿道充血结合治疗女性IC患者的疗效和安全性.
评估这种联合治疗对症状评分,疼痛水平和功能性膀容量的影响.

主要方法:

根据美国泌尿病学协会指导方针诊断的79名女性IC患者的回顾性分析.
治疗涉及12个月的静脉肝素/化利多卡因,有或没有水分扩张和通过尿道充血 (HD/TF).
患者在基线和随访间隔 (1, 6, 12 个月) 中使用奥利里-桑特IC症状指数 (ICSI),IC问题指数 (ICPI),疼痛视觉模拟尺度 (VAS) 和功能性膀容量 (FBC) 来评估患者.

主要成果:

与基线相比,联合治疗导致ICPI,ICSI,VAS和FBC显著改善 (P <0.05).
与非HD/TF组相比,HD/TF组的患者表现出更早的症状改善和更显著的VAS和FBC变化 (P <0.05).
由于癌症或治疗失败,四名患者 (5.1%) 需要切除囊;其余患者显示持续改善.

结论:

内肝素/化利多卡因与HD/TF相结合,是治疗间歇性囊炎的有效方法.
这种组合疗法可以作为主要治疗选择,可能降低医疗保健成本.
对于那些能容忍手术的患者来说,HD/TF可以被视为辅助疗法.

关键词:

水分分散是一种水分分散.间歇性囊炎间歇性囊炎通过体内灌注.通过尿道的光.

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